Online courses directory (190)

This chemistry survey is designed to introduce students to the world of chemistry.  The principles of chemistry were first identified, studied, and applied by ancient Egyptians in order to extract metal from ores, make alcoholic beverages, glaze pottery, turn fat into soap, and much more.  What began as a quest to build better weapons or create potions capable of ensuring everlasting life has since become the foundation of modern science.  Take a look around you: chemistry makes up almost everything you touch, see, and feel, from the shampoo you used this morning to the plastic container that holds your lunch.  In this course, we will study chemistry from the ground up, learning the basics of the atom and its behavior.  We will use this knowledge to understand the chemical properties of matter and the changes and reactions that take place in all types of matter.

In this second semester course, we will cover a wide-ranging field of topics, learning everything from the equation that made Einstein famous to why you can’t replace a dead car battery with a household battery. In General Chemistry I (CHEM101 [1]), we studied the basic tools you need to explore different fields in chemistry, such as stoichiometry and thermodynamics.  This second-semester course will cover several of the tools needed to study chemistry at a more advanced level.  We will identify the factors that affect the speed of a reaction, learn how an atom bomb works on a chemical level, and discover how chemistry powers a light bulb.  Topics in advanced organic and inorganic chemistry courses will build upon what you learn in this class.  We will end with discussion of organic chemistry, a topic that is as important to biology as it is to chemistry. [1] http:///courses/chem101/…

Organic chemistry is a branch of chemistry that focuses on a single element: carbon!  Carbon bonds strongly with other carbon atoms and with other elements, forming numerous chain and ring structures.  As a result, there are millions of distinct carbon compounds known and classified.  The vast majority of the molecules that contain carbon are considered organic molecules, with few debatable exceptions such as carbon nanotubes, diamonds, carbonate ions, and carbon dioxide.  Carbon is central to the existence of life as it is an essential component of nucleic acids (DNA and RNA), sugars, lipids, and proteins.  A well-rounded student of science must take courses in organic chemistry to understand its application to various topics, such as the study of polymers (plastics and other materials), hydrocarbons, pharmaceuticals, molecular biology, biochemistry, and other life sciences. In the first semester of organic chemistry, you will learn the basic concepts needed to understand the three-dimensional structu…

This course is a continuation of CHEM103 [1]: Organic Chemistry I.  As you progress through the units below, you will continue to learn the different chemical reactions characteristic of each family of organic compounds.  We will focus on four most important classes of reactions: electrophilic substitution at aromatic rings, nucleophilic addition at carbonyl compounds, hydrolysis of carboxylic acids, and carbon-carbon bond formation using enolates.  The enolate portion of this course will cover the reactivity of functional groups. We will also look at synthetic strategies for making simple, small organic molecules, using the knowledge of organic chemistry accumulated thus far.  At the end of this course, you will possess the tools you need to plan the synthesis of fairly complicated molecules, like those used in pharmaceutics.  From the perspective of a synthetic organic chemist, the two most challenging aspects of synthesizing drug molecules are the incorporation of  "molecular rings" (rings of 5, 6,…

Physics 101 is the first course in the Introduction to Physics sequence. In general, the quest of physics is to develop descriptions of the natural world that correspond  closely to actual observations.  Given this definition, the story behind everything in the universe is  one of physics.  In practice,  the field of physics is more often limited to the discovery and refinement of the basic laws that underlie the behavior of matter and energy.  While biology is founded upon physics, in practice, the study of biology generally assumes that the present understanding of physical laws is accurate.  Chemistry is more closely dependent on physics and   assumes that physical laws provide accurate predictions.  Engineering, for the most part, is applied physics. In this course, we will study physics from the ground up, learning the basic principles of physical laws, their application to the behavior of objects, and the use of the scientific method in driving advances in this knowledge.  This first course o…

The physics of the universe appears to be dominated by the effects of four fundamental forces: gravity, electromagnetism, weak nuclear forces, and strong nuclear forces.  These forces control how matter, energy, space, and time interact to produce our physical world.  All other forces, such as the force you exert in standing up, are ultimately derived from these fundamental forces. We have direct daily experience with two of these forces: gravity and electromagnetism.  Consider, for example, the everyday sight of a person sitting on a chair.  The force holding the person on the chair is gravitational, and that gravitational force balances with material forces that “push up” to keep the individual in place.  These forces are the direct result of electromagnetic forces on the nanoscale.  On a larger stage, gravity holds the celestial bodies in their orbits, while we see the universe by the electromagnetic radiation (light, for example) with which it is filled.  The electromagnetic force also makes…

As you learned in BIO101 [1], the cell is the fundamental unit of life; in fact, the smallest living organisms are composed of a single cell. We have learned that, despite their small size, cells are far from simple, and we have only recently begun to understand just how complex they are. This course will present you with a detailed overview of a cell’s main components and functions. Most of the units will cover topics familiar to you from BIO101, such as mitosis or the cell nucleus, but will explore them in greater depth. The course is organized roughly into four major areas: the cell membrane, cell nucleus, cell cycle, and cell interior. We will approach most of these topics straightforwardly, from a molecular and structural point of view. [1] http://www.saylor.org/courses/bio101a/…

A thorough understanding of the systems of the body and the ways in which they fit together is imperative for study in many fields of biological inquiry, including medicine, physiology, developmental studies, and biological anthropology.  This course will provide you with an overview of the body from a systemic perspective.  Each unit will focus on one system, or network of organs that work together to perform a particular function.  At the end of this course, we will review the body from an integrative perspective, creating a more realistic vision of the ways in which the systems overlap.  We will also discuss current body imaging techniques and learn how to correctly interpret the images in order to put our newly-gained anatomical knowledge to practical use. This is a terminology-heavy course.  We will identify tissues and organ systems according to their functional and regional contexts, but information concerning the processes by which the tissues and organ systems actually function will be covered…

This lab course supplements BIO302: Human Anatomy [1].  Although we cannot virtually replicate the lab experience, this “lab” will familiarize you with scientific thinking and techniques and will enable you to explore of some key principles of human anatomy. The material in this lab supplement relates to the material covered in the lecture and reading portion of the course.  While that portion focuses more on large-picture concepts, here we will focus more on visual understanding, manipulation, and practical use of your knowledge.  You will review the anatomy and histology of the organs by using images of models, microscopic slides, and videos on cat and sheep dissections.  Then you will be asked to assess your knowledge, which eventually can be put to practical or experimental use.  Working though this lab supplement, you will realize that you must memorize new terms and locate different structures and organs, which can only be achieved by repetition and practice. Note: This course makes use of…

Neurobiology is all about the biology of our nervous system, from the spinal cord to the brainand everything in between. The nervous system allows us to have conscious thoughts, enables us to learn, and gives us voluntary control of our muscles. Our understanding of neuroscience begins with the ancient Egyptians, who practiced surgical drilling to treat certain neurological disorders. The earliest philosophers believed that the heart (not the brain) was the center of consciousness and intelligence. As scientific knowledge matured and developed, philosophers disproved that belief but discovered that there is much more to neurobiology than “the brain.” Researchers found that there are literally hundreds of billions of nerves and other cells that cooperate and share information to make the nervous system work. Accordingly, neurobiology is an extremely complex field of study. This course is designed to provide you with an overview of the most important areas of neurobiological study. We will not pay much…

Human physiology is the study of the body’s processes, also known as functions. You already have experience with this subject, because you are a human and perform numerous functions each day to maintain your body’s balance or homeostasis. For example, gas exchange in your lungs provides the body’s cells with adequate oxygen supply needed to survive and carry out metabolic processes. Digestion of food components in your mouth, stomach, and small intestines breaks larger substances into molecules that can be absorbed in the small intestines and used for energy. White blood cells attack foreign bodies, such as bacteria and cells containing viruses to keep you free from infection. As you might expect, an understanding of physiology is paramount if you wish to pursue studies in health care, development, or even behavior. A doctor needs to understand how to relate a urine sample to kidney function. A nurse needs to know the importance of electrocardiogram results and heart activity. A medical laboratory sci…

This lab course supplements BIO304: Human Physiology [1].  Although we cannot virtually replicate the lab experience, this “lab” will familiarize you with scientific thinking and techniques and will enable you to explore of some key principles of human physiology. The material in this lab supplement relates to the material covered in the lecture and reading portion of the course.  While the lecture and reading portion focuses on big-picture concepts, here we will focus more on visual understanding, manipulation, and practical use of your knowledge.  You will review the physiology of the organ systems by using images of models, experiments, and videos.  Then you will be asked to assess your knowledge, which eventually can be put to practical or experimental use. Co-requisite: BIO304: Human Physiology [2]. [1] http://www.saylor.org/courses/bio304/ [2] http://www.saylor.org/courses/bio304/…

Genetics is the branch of biology that studies how traits are passed on from one generation to the next and why there are similarities and differences between related individuals. Prior to the discovery of genes, scientists knew that parents passed something down to their offspring, but they did not know how or what. Gregor Mendel’s famous experiments with peas indicated that certain features, such as pea texture and flower color, are encoded by two sets of traits and that the parental traits can be separated. Decades later, scientists discovered that parents passed down DNA, which was present in chromosomes. Since the discovery of DNA, we have come to appreciate the importance of chromosomes. Genomics is a relatively new field with the bold aim of understanding the function of every single gene in a genome, including the human genome. This field took off with the completion of the first sequenced genome, and after the completion of the Human Genome Project, it has attracted increasing research. Mendelian…

Botany is the study of plants.  Because species in the plant kingdom have characteristics that make them distinct from any other form of life, they are particularly interesting subjects for the study of evolution and physiology.  For example, whereas most organisms are dependent on other organisms for energy, plants can capture energy directly from photons of light and convert it into a usable form through the process of photosynthesis.  For this reason, plants are referred to as the “producers” in a habitat.  Unlike the cells of other organisms, plant cells have rigid cell walls constructed from the inside out (rather than the outside in) during mitosis and cytokinesis.  Plants also have a variety of unique reproductive and dispersal mechanisms that allow them to quickly adapt to, occupy, and invade far-flung areas, despite their general immobility. In this course, you will learn the basics of plant biology.  We will begin with plant anatomy, learning the names and functions of all of the parts o…

Even in ancient times, scholars believed that diseases could be spread by organisms too small to be seen by the naked eye. Before we discovered that bacteria cells were the real culprits, many attributed disease to other sources. Now that scientists have definitively identified the microscopic causes of various infectious diseases, microbiology, or the study of microscopic-sized organisms, has become an increasingly important field in biology and in the larger biomedical community. Most microbes are harmless. Some of them are essential for life on Earth, e.g. through their ability to fix nitrogen. Biotechnology, which is truly the industry of our times, takes advantage of microbes for the production of a variety of complex substances, and it also mass-produces natural and engineered microbes for human use. This course will cover a range of diverse areas of microbiology, including virology, bacteriology, and applied microbiology. This course will focus on the medical aspects of microbiology, as medical res…

Marine Biology is the study of ocean life.  As you might expect, life in salt water is vastly different from life in a terrestrial or freshwater environment due to factors like salinity, water circulation, and atmospheric pressure.  How, for example, can organisms living in salt water avoid dehydration?  How do organisms living in the depths of the ocean handle the immense pressure?  How do the environmental factors in marine communities affect biodiversity?  How do some animals manage to alternate between the demands of terrestrial life and the demands of marine life?  In this course, you will learn the answers to these questions and more.  This course will touch on a number of different subfields of biological study (including biochemistry, physiology, zoology, botany, and ecology) within the context of the ocean environment. You will start by learning about the ocean itself and its physical properties, as these properties influence the abundance, distribution, diversity, physiology, and behavior o…

Zoology is the scientific study of diversity of animal life, classification, physiology, behavior, and evolution. Unicellular organisms have evolved into complex multicellular forms. Organisms, both unicellular and multicellular, in various complex shapes and sizes are found in almost every habitat and environment. The field of zoology includes many subfields of biology as well as a vast diversity of unicellular and multicellular organisms. Animals first appeared in the fossil record an estimated 600 million years ago as multicellular protozoa. Over the next 70 million years, they radiated into an incredible number of different invertebrate phyla (which represent the majority of animal groups and species), and in the next 150 million years, vertebrate and invertebrate species began to colonize the land. Though the history of animals is extensive and the fossil record at times is conflicted and vague, understanding the historical connections between animals is important in order to understand modern-day rela…

Developmental biology asks questions about how organisms come into being, how life forms, and how complex structures develop and are differentiated.  These fundamental questions have been the subject of research for centuries; accordingly, this course you will teach you not only about the beginnings of organisms, but about the beginnings of developmental biology as a science.  Currently, developmental biologists use a range of tools and research focifrom molecular techniques to surgical manipulations to chemical and environmental studiesto answer these questions.  Their approaches are multi-faceted because developmental biology itself addresses topics of importance to a wide range of fields, from molecular biology to neuroscience to evolutionary biology. In this course, you will learn about the field of developmental biology from its origins to the present day.  We will take a look at historical experiments as well as modern techniques and the mechanisms of development.  You will follow a variety of me…

Molecular biology studies the molecular mechanisms of life, particularly those responsible for genes and their expression.  In the center of molecular biology are the nucleic acids, DNA and RNA, and how they contribute to the synthesis of proteins. After a historical introduction (Unit 1), this course describes the basic types of DNA and RNA structure and the molecular interactions that shape them (Unit 2).  Unit 3 describes how DNA is packaged within the cellular nucleus as chromosomes; in eukaryotes the DNA coils around histones to form nucleosomes that comprise the chromatin of the chromosomes.  The next three units describe the core processes of molecular biology: replication of DNA (Unit 4), transcription of DNA into messenger RNA (Unit 5), and translation of messenger RNA into a protein (Unit 6).  These are followed by modifications of these basic processes: regulation of gene expression (Unit 7), DNA mutation and repair (Unit 8), and DNA recombination and transposition (Unit 9). The course conclu…

One of the best ways to understand the present is to understand the past. Evolutionary Biology is the study of the changes in life forms over time - changes that have occurred over millions of years as well as those that have occurred over just a few decades. In this course, we will look at the various mechanisms of evolution, how these mechanisms work, and how change is measured. The concepts you learn in this course will serve as a foundation for studying fossil records and current classification schemes in biology. We will begin the course by reviewing the evolutionary concepts of selection and speciation. We will then learn to measure evolutionary change through comparisons with the Hardy-Weinberg Equilibrium, to understand the process of change through Game Theory, and to interpret and classify changes by creating phylogenies. The course will wrap up with a look at the history of life according to the fossil record and a discussion of the broad range of life forms as they are currently classified. At the…