Courses tagged with "Information Theory" (117)
This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological function for tissues and organs.
An advanced course covering anatomical, physiological, behavioral, and computational studies of the central nervous system relevant to speech and hearing. Students learn primarily by discussions of scientific papers on topics of current interest. Recent topics include cell types and neural circuits in the auditory brainstem, organization and processing in the auditory cortex, auditory reflexes and descending systems, functional imaging of the human auditory system, quantitative methods for relating neural responses to behavior, speech motor control, cortical representation of language, and auditory learning in songbirds.
This course focuses on computational and experimental analysis of biological systems across a hierarchy of scales, including genetic, molecular, cellular, and cell population levels. The two central themes of the course are modeling of complex dynamic systems and protein design and engineering. Topics include gene sequence analysis, molecular modeling, metabolic and gene regulation networks, signal transduction pathways and cell populations in tissues. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling.
The aim of this class is to introduce the exciting and often under appreciated discoveries in RNA biology by exploring the diversity of RNAs—encompassing classical molecules such as ribosomal RNAs (rRNAs), transfer RNAs (tRNAs) and messenger RNAs (mRNAs) as well as newer species, such as microRNAs (miRNAs), long-noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). For each new class of RNA, we will evaluate the evidence for its existence as well as for its proposed function. Students will develop both a deep understanding of the field of RNA biology and the ability to critically assess new papers in this fast-paced field.
This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Biomimetics is based on the belief that nature, at least at times, is a good engineer. Biomimesis is the scientific method of learning new principles and processes based on systematic study, observation and experimentation with live animals and organisms. This Freshman Advising Seminar on the topic is a way for freshmen to explore some of MIT's richness and learn more about what they may want to study in later years.
The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.
Mechanical forces play a decisive role during development of tissues and organs, during remodeling following injury as well as in normal function. A stress field influences cell function primarily through deformation of the extracellular matrix to which cells are attached. Deformed cells express different biosynthetic activity relative to undeformed cells. The unit cell process paradigm combined with topics in connective tissue mechanics form the basis for discussions of several topics from cell biology, physiology, and medicine.
This is an undergraduate introductory laboratory subject in ocean chemistry and measurement. There are three main elements to the course: oceanic chemical sampling and analysis, instrumentation development for the ocean environment, and the larger field of ocean science.
This course is offered through The MIT/WHOI Joint Program. The MIT/WHOI Joint Program is one of the premier marine science graduate programs in the world. It draws on the complementary strengths and approaches of two great institutions: the Massachusetts Institute of Technology (MIT) and the Woods Hole Oceanographic Institution (WHOI).
This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT.
Acknowledgements
The laboratory manual and materials for this course were prepared by Dr. Katherine J. Franz and Dr. Kevin M. Shea with the assistance of Professors Rick L. Danheiser and Timothy M. Swager. Materials have been revised by Dr. J. Haseltine, Dr. Kevin M. Shea, Dr. Sarah A. Tabacco, Dr. Kimberly L. Berkowski, Anne M. (Gorham) Rachupka, and Dr. John J. Dolhun.
WARNING NOTICE
The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented.
Legal Notice
This course covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. The course is structured as a series of lectures and tutorials in which clinical cases are discussed with faculty tutors.
Lecturers
Frederick W. Alt
Marcus Altfeld
Paul Anderson
Jon C. Aster
Hugh Auchincloss
Steven P. Balk
Samuel M. Behar
Richard S. Blumberg
Francisco Bonilla
Bobby Cherayil
Benjamin Davis
David Hafler
Nir Harcohen
Bruce Horwitz
David M. Lee
Andrew Lichtman
Diane Mathis
Richard Mitchell
Hidde Ploegh
Emmett Schmidt
Arlene Sharpe
Megan Sykes
Shannon Turley
Dale T. Umetsu
Ulrich von Andrian
Bruce Walker
Kai Wucherpfennig
Ramnik Xavier
Sarah Henrickson
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This seminar will focus on three sports: swimming, cycling and running. There will be two components to the seminar: classroom sessions and a "laboratory" in the form of a structured training program. The classroom component will introduce the students to the chemistry of their own biological system. With swimming, running and cycling as sample sports, students are encouraged to apply their knowledge to complete a triathlon shortly after the term.
This seminar will focus on three sports: swimming, cycling and running. There will be two components to the seminar: classroom sessions and a "laboratory" in the form of a structured training program. The classroom component will introduce the students to the chemistry of their own biological system. With swimming, running and cycling as sample sports, students are encouraged to apply their knowledge to complete a triathlon shortly after the term.
The seminar is designed to look at the science of triathlons and sports from a molecular/chemical biological point of view. We will be able to use our own bodies to see how exercise affects the system, through observations written in a training journal. We will also improve the overall fitness of the class through maintaining a physical fitness program over the course of the term. The end of the term will have us all participate in a mini-triathlon.
This course applies the tools of anthropology to examine biology in the age of genomics, biotechnological enterprise, biodiversity conservation, pharmaceutical bioprospecting, and synthetic biology. It examines such social concerns such as bioterrorism, genetic modification, and cloning. It offers an anthropological inquiry into how the substances and explanations of biology—ecological, organismic, cellular, molecular, genetic, informatic—are changing. It examines such artifacts as cell lines, biodiversity databases, and artificial life models, and using primary sources in biology, social studies of the life sciences, and literary and cinematic materials, and asks how we might answer Erwin Schrodinger's 1944 question, "What Is Life?" today.
This course provides a detailed overview of the chemical transformations that control the abundances of key trace species in the Earth's atmosphere. Emphasizes the effects of human activity on air quality and climate. Topics include photochemistry, kinetics, and thermodynamics important to the chemistry of the atmosphere; stratospheric ozone depletion; oxidation chemistry of the troposphere; photochemical smog; aerosol chemistry; and sources and sinks of greenhouse gases and other climate forcers.
The course focuses on casting contemporary problems in systems biology and functional genomics in computational terms and providing appropriate tools and methods to solve them. Topics include genome structure and function, transcriptional regulation, and stem cell biology in particular; measurement technologies such as microarrays (expression, protein-DNA interactions, chromatin structure); statistical data analysis, predictive and causal inference, and experiment design. The emphasis is on coupling problem structures (biological questions) with appropriate computational approaches.
Humans are social animals; social demands, both cooperative and competitive, structure our development, our brain and our mind. This course covers social development, social behaviour, social cognition and social neuroscience, in both human and non-human social animals. Topics include altruism, empathy, communication, theory of mind, aggression, power, groups, mating, and morality. Methods include evolutionary biology, neuroscience, cognitive science, social psychology and anthropology.